Carbonyl Chemistry

Conjugate Addition-Alkylation

Catalytic Asymmetric TandemTransformations Triggered by Conjugate Additions
  Guo, H.-C.; Ma, J.-A. Angew. Chem. Int. Ed. 2006, 45, 354-66.

Green, Crabbé, Tetrahedron Lett. 1976, 4867.


 

Sometimes it is more efficient to capture the intermediate enolate as an enol silyl ether, with a seprate step for the alkylation - Huang, Forsyth, J. Org. Chem. 1995, 60, 5746.


 

Danishefsky, Vaughan, Gadwood, Tsuzuki, J. Am. Chem. Soc. 1981, 103, 4136.


 

Kibayashi J. Am. Chem. Soc. 2004, 126, 16553


 

Tamura, JCS Perk. Trans. I 1982, 1099.


 

Conjugate Reduction-Alkylation

Ganem, J. Org. Chem. 1976, 41, 2195.


 

Conjugate Addition-Acylation

Jones, Tetrahedron Lett. 1993, 34, 8553.