Total synthesis of Aflavazole (Part 2) New:
| Reference: | Li, H.; Chen,Q.; Lu, X.; Li, A. J. Am. Chem. Soc. 2016, 138, 15555-15558. DOI (Part 1) |
| Reactions: | Julia-Kocienski • Li-Sulfone+Aldehyde • Ketone → EnolTriflate • EnolTriflate → Alkyne • Ketone → Alkyne • O-SiMe3 → O-H • Prins • Cyclohexene • Pd/Sn-Aryl+Vinyl-X • Electrocyclic-6π • Benzene synthesis • Benzyl-OR → Benzyl-H • N-SO2R → N-H • |
| Reagents: | NaN(SiMe3)2 • Tf2NPh • Fluoride, R4N+ • Pd(PPh3)4 • LiN(SiMe3)2 • LiCHR-Sulfonyl • DDQ • HSiEt3 • TiCl4 • |