Total synthesis of Amouromine:
| Reference: | Marsden, S. P.; Depew, K. M.; Danishefsky, S. J. J. Am. Chem. Soc. 1994, 116, 11143. DOI |
| Reactions: | CarboxAcid → CarboxAmide • Peptide • Sn-Allyl+Benzyl-X • Selenoamidation • Amine-5 • Bicyclo(330)-aza • N-Boc → N-H • CarboxEster → CarboxAcid • N-Boc → N-H • Lactam-6 • |
| Reagents: | Hydroxide, potassium • SiMe3-I • BOP • SiMe3-I • Imidazole • MeOTf • Allyl-SnR3 • |