Total synthesis of Bergamotene, β-trans:
| Reference: | Corey, E. J.; Desai, M. C. Tet. Lett. 1985, 26, 3535. DOI |
| Reactions: | Ketone enolate+CO2 • Wittig-methyl • Wolff-Kishner • Ketone → CH2 • Ketene Cycloaddition • Cyclobutane • Cyclohexanone • CarboxCl → Ketene • Ketene synthesis • Bicyclo(311) • CarboxAcid → CarboxCl • |
| Reagents: | LiNiPr2 • CO2 • PPh3=CH2 • Oxalyl chloride • Hydrazine • KOtBu • LiN(SiMe3)2 • NEtiPr2 • |