Total synthesis of Bursehemin:
| Reference: | Baran, P. S.; DeMartino, M. P. Angew. Chem IE. 2006, 45, 7083. DOI |
| Reactions: | CarboxEster enolate Oxidation • CarboxAmide enolate Oxidation • Oxidative coupling enolate • CarboxAmide enolate(Evans) coupling • CarboxAmide(Evans) → Alkyl-OH • Lactone-5 • |
| Reagents: | Chiral auxiliary (amide-Evans) • LiNiPr2 • Cu(OAc)2 • BH4-Li+ • DBU • |