Total synthesis of Cadinene Dihydrochloride:
| Reference: | Soffer, M. D.; Gunay, G. E.; Korman, O.; Adams, M. B. Tetrahedron Lett. 1963, 389. DOI |
| Reactions: | Diels-Alder, Enone • Bicyclo(440) • Ketone epimerization • Ketone+Li-Alkyl • Li-Me+Ketone • Alkyl-OH → Alkyl-Cl • EnolEther → Ketone • |
| Reagents: | Me-Li • Butadiene, 2-OR • |