Total synthesis of Cantharidin (Dauben):
| Reference: | Dauben, W. G.; Kessel, C. R.; Takemura, K. H. J. Am. Chem. Soc. 1980, 102, 6893–6894. DOI |
| Reactions: | Diels-Alder, Maleic anhydride • Furan cycloaddition • Bicyclo(221)-oxa • Hydrogenation alkene • Alkyl-SR → Alkyl-H • |
| Reagents: | RaNi • H2, Pd • Maleic anhydride • High pressure • |