Total synthesis of Carvone (Vig):
| Reference: | Vig, O. P. ; Sharma, S. D.; Chander, S.; Raj, I. Ind. J. Chem. 1966, 4, 275 |
| Reactions: | Allylic oxidation → Enal • Aldol-Acid → Enone • Cyclohexenone • Claisen-EnolEther • Alkene isomerization • Mg-Alkyl+CarboxCl • CarboxCl+Mg-R • Enal → Allyl-OH • Ketal → Ketone • Enone → Ketal • |
| Reagents: | Alkyl-MgX • Glycol • SeO2 • AlH4-Li+ • Hg(OAc)2 • Vinyl-OR • TsOH • Ethyl vinyl ketone • |