Total synthesis of Cryptocarya Diacetate:
| Reference: | Boxer, M. B.; Yamamoto, H. J. Am. Chem. Soc., 2007, 129, 2762-2763 DOI |
| Reactions: | O-H → O-C(O)R • Mukaiyama Aldol • Aldol-Si • Aldehyde+EnolSilane • RCM → Lactone • Lactone-6 • Mg-Allyl+Aldehyde • Aldehyde+Mg-R • O-SiMe2tBu → O-H • O-Si(SiMe3)3 → O-H • O-H → O-C(O)R • |
| Reagents: | Vinyl-OR • Tf2NH • Allyl-MgX • Acryloyl-Cl • Grubbs II • HF·Py • Acetic anhydride • |