Total Syntheses

Reaction scheme for total synthesis of the natural product α-Curcumene
Total synthesis of α-Curcumene:
Reference:Krapcho, A. P.; Jahngen, Jr. J. Org. Chem. 1974, 39, 1322. DOI
Reactions:Decarboxylation β-lactone • Lactone-4 • CarboxAcid enolate+Aldehyde •
Reagents:LiNiPr2 • Sulfonyl chloride, benzene • Pyridine •