Total synthesis of Disparlure:
| Reference: | Li, L. H.; Wang, D.; Chan, T. H. Tetrahedron Lett. 1997, 38, 101. DOI |
| Reactions: | Sharpless epoxidation • Carbocupration Alkyne • Cu-Alkyl+Alkyne • Mg-R → Cu-R • Cu-Vinyl+Alkyl-X • Alkyl-X+Cu-R • Si-Oxiranyl → H-Oxiranyl • |
| Reagents: | Alkyl-MgX • CuI • P(OMe)3 • Vinyl-Cu • NiBr • Tartrate, diisopropyl • Hydroperoxide, tbutyl - Ti • Fluoride, R4N+ • |