Total synthesis of Clausenane New:
| Reference: | Kondo, K.; Matsumoto, M. Tetrahedron Lett. 1976, 17, 4363-4366. DOI |
| Reactions: | Mg-Vinyl+Aldehyde • Singlet oxygen+Diene • Furan synthesis • Iodoetherification • Ether-5 • Li-Dithiane+Alkyl-X • Alkyl-X+Li-R • Li-Dithiane+Alkyl-X • Alkyl-X+Li-R • Ketal(thio) → Ketone • Dehydration → Ene • Li/H → Li-Dithiane • |
| Reagents: | Butadiene • O2 (singlet) • Rose Bengal • LiOtBu • H2SO4 • NIS • Bicarbonate, sodium • HMPA (solvent) • BuLi(n) • HMPA (solvent) • AgNO3 • NCS • Bisulfate, potassium • |