Total Syntheses

Reaction scheme for total synthesis of the natural product Ipsdienol (Sakurai)
Total synthesis of Ipsdienol (Sakurai):
Reference:Hosomi, A.; Araki, Y.; Sakurai, H. J. Org. Chem. 1983, 48, 3122. DOI
Reactions:Si-Allyl+Aldehyde • Aldehyde+Si-R • O-SiMe3 → O-H •
Reagents:Allyl-SiR3 • Fluoride, R4N+ • HCl, MeOH • Fluoride, R4N+ • HCl, MeOH •