Total synthesis of Myodesmone:
| Reference: | Dieter, R. K.; Dieter, J. W. Chem. Commun. 1983, 1378DOI |
| Reactions: | ConjAdd-Silylation • Cu-Me+Enone • Ketene acetal(thio) → CarboxAcid • Cu-Alkyl+CarboxEster(thio) • CarboxEster(thio)+Cu-R • CompE+-CarboxEster/Ketone+M-R • EnolSilane → Ketone enolate • Ketone enolate+CS2 • Li-Aryl+Ketone • Enone+Li-R • CarboxAcid(dithio) → Ketene acetal(thio) • |
| Reagents: | Me-Cuprate • SiMe3-Cl • Me-Li • CS2 • LiN(SiMe3)2 • MeI • Furyl-Li • HBF4 • Alkyl-Cu • HMPA (solvent) • |