Total synthesis of Parinaric Acid, β:
| Reference: | Lee, S. J.; Gray, K. C.; Paek, J. S.; Burke, M. D. J. Am. Chem. Soc. 2008, 130, 466. DOI |
| Reactions: | Protecting group - Boronate • Vinyl-Br → Vinyl-B • Pd/B-B+Vinyl-X • Pd/B-Vinyl+Vinyl-X • Pd/B-Vinyl+Vinyl-X • CompNu-B-Vinyl/B-Vinyl+R-I • Pd/B-Vinyl+Vinyl-X • |
| Reagents: | Vinyl-Br • Vinyl-BR2 • Vinyl-BR2 • PdCl2(MeCN)2 • Vinyl-BR2 • Vinyl-I • Pd(OAc)2 • Vinyl-BR2 • Pd(OAc)2 • Hydroxide, sodium • Vinyl-BR2 • Vinyl-I • Pd(OAc)2 • Hydroxide, sodium • B2(Pinacol)2 • Lutidine • |