Total synthesis of Patchouli Alcohol:
| Reference: | Magee, T. V.; Stork, G.; Fludzinski, P. Tet. Lett. 1995, 36, 7607. DOI |
| Reactions: | Li-Allenyl/Propargyl+Ketone • Diels-Alder, EneSulfoxide • Sulfoxide-Ei → Ene • Bicyclo(222) • Alkyne isomerization • Hydrogenation alkene • Radical cyclization(Vinyl) • Bicyclo(331) • Sn-Vinyl → H-Vinyl • Alkene → Alkane • CompRed-Alkene/Alkyne+M° • Li-R → Mg-R • |
| Reagents: | EneSulfoxide • Allenyl-Li • Ca°/NH3 • BuLi(tert) • H2, Pd • SiO2 • MgBr2 • HSnBu3 • AIBN • |