Total synthesis of Pleraplysillin-1:
| Reference: | Scott, W. J.; Crisp, G. T.; Stille, J. K. J. Am. Chem. Soc., 1984, 106, 4630. DOI |
| Reactions: | Ketone → EnolTriflate • Cu-Vinyl+Alkyl-X • Allyl-X+Cu-R • Pd/Sn-Vinyl+Vinyl-X • ConjReduct-Triflation • ConjReduct Enone • |
| Reagents: | BH(sBu3)-Li+ • Tf2NPh • Vinyl-Cu • Vinyl-SnR3 • Pd(PPh3)4 • Chloride, lithium • |