Total synthesis of Drimenin:
| Reference: | Jallali-Naini, M.; Boussac, G.; Lemaitre, P.; Larcheveque, M.; Guillerm D. Lallemand, J. Y.; et al. Tetrahedron Lett. 1981, 22, 2995. DOI |
| Reactions: | CarboxEster → Alkyl-OH • Hydrogenation Diene • CompRed-Alkene/Enoate+H2 • Alkene isomerization • CarboxEster epimerization • Diels-Alder, Yne • Bicyclo(440) • Thorpe-Ingold • EnoateEster → Allyl-OH • CompRed-CarboxEster/CarboxEster+M-H • Lactone-5 • Allyl-OH → Enal • |
| Reagents: | LiNiPr2 • H2SO4 • H2, Pd • AlH4-Li+ • DMSO, (COCl)2 (Swern) • NEt3 • AlHiBu2 • TsOH • KOtBu • LiNiPr2 • Acetylene dicarboxylate • |