Total synthesis of Santalene, β (Corey):
| Reference: | Corey, E. J.; Hartmann, R.; Vatakencherry, P. A. J. Am. Chem. Soc. 1962, 84, 2611. DOI |
| Reactions: | Dehydration → Ene • Ketone enolate+Me-I • Bicyclo(221) • Ketone enolate+Alkyl-X • Alkyl-X+Enolate • Ketone → C=CH2 • Li-Me+Ketone • Ketone+Li-Alkyl • |
| Reagents: | NaNH2 • MeI • NaNH2 • Me-Li • SOCl2 • |