Total synthesis of Sparteine (VanTamelen):
| Reference: | VanTamelen, E.; Foltz, R. L. J. Am. Chem. Soc. 1960, 82, 2400. DOI |
| Reactions: | Mannich • Amine → Imine • Mannich • Amine-6 • Bicyclo(331)-aza • Wolff-Kishner • Ketone → CH2 • |
| Reagents: | Acetone (react) • Formaldehyde • Piperidine • Hg(OAc)2 • Hydrazine • Hydroxide, potassium • |