Total Syntheses

Reaction scheme for total synthesis of the natural product Spongistatin 2 - (Part 7) (Smith) <b><i><font color=green>New</font></i></b>
Reference:Smith, A. B., III; Doughty, V. A.; Lin, Q.; Zhuang, L; McBriar, M. D.; Boldi, A. M.; Moser, W. H.; Murase, N.; Nakayama, K.; Sobukawa, M.; Angew. Chem. Int. Ed. 2001, 40, 191. DOI-1 Smith, A. B., III; Lin, Q.; Doughty, V. A.; Zhuang, L; McBriar, M. D.; Kerns, J. K.; Brook, C. S.; Murase, N.; Nakayama, K. Angew. Chem. Int. Ed. 2001, 40, 196. DOI-2 (Part 1) (Part 2) (Part 3) (Part 4) (Part 5) (Part 6)
Reagents:Chiral auxiliary (boronate) •