Total synthesis of Thromboxane A2 Model:
| Reference: | Bhagwat, S. S.; Hamann, P. R.; Still, W. C. Tetrahedron Lett., 1985, 26, 1955. DOI |
| Reactions: | Reformatsky • CarboxEster enolate+Enal • Enal+Enolate • Radical reduction(C-Br) • Alkyl-X → Alkyl-H(2°) • Hydroboration → Alkyl-OH • Mitsunobu → OR • Alkyl-OH → Alkyl-OR • |
| Reagents: | Zn° • Bromoacetate • BH2(Thexyl) • H2O2, NaOH • PPh3, DEAD • HSnBu3 • |