Total synthesis of Thujopsene (Buchi) New:
| Reference: | Büchi, G.; White, J. D. J. Am. Chem. Soc. 1964, 86, 2884-2887. DOI |
| Reactions: | O-H → O-Vinyl • Claisen-EnolEther • Aldehyde → Acetal(Me) • Aldol-Acid → Enal • Aldehyde → Hydrazone • Carbene Cycloaddition • Diazoalkane • |
| Reagents: | Vinyl-OR • Hg(OAc)2 • Orthoformate • TsOH • HOEt (react)} • Vinyl-OR • ZnCl2 • Acetic acid • Acetate, sodium • NaH • |