Total synthesis of Turmerone, Ar- (Grieco):
| Reference: | Grieco, P. A.; Finkelhor, R. S. J. Org. Chem. 1973, 38, 2909. DOI |
| Reactions: | KetoPhosphonate dianion+Alkyl-X • Ketone enolate+Alkyl-X • Benzyl-X+Enolate • HWE → Enone • |
| Reagents: | P(O)(OR)2CH2-C(O)R' • NaH • BuLi(n) • Benzyl-X • P(O)(OR)2CH2-C(O)R' • Acetone (react) • NaH • |