Total synthesis of Vibralactone (Nelson) New:
| Reference: | Nistanaki, S. K.; Boralsky, L. A.; Pan, R. D.; Nelson, H. M. Angew. Chem. Int. Ed. 2019, 58, 1724-1726. DOI |
| Reactions: | Cu-Vinyl+Alkyl-X • Photochemistry electrocyclic • Electrocyclic-4π • Cyclobutane • Lactone-4 • Bicyclo(220)-oxa • Cyclopropanation Diazoester • Cyclopropane isomerization • CarboxEster → Alkyl-OH • |
| Reagents: | Photochemistry • Diazoacetate • Rh2(esp)2 • DBU • AlHiBu2 • Me-Cuprate • Allyl-Br • |